Ioanna Kousiappa

CSMM Academic Staff

Current Position

Post-doctoral Fellow, Neurology Clinic B’, The Cyprus Institute of Neurology and Genetics


  • BSc in Biological Sciences, University of Patra, Greece, 2004         
  • MSc in Molecular Biology, Dep. of Biological Sciences, University of Cyprus, 2006       
  • PhD in Molecular Biology, Dep. of Biological Sciences, University of Cyprus, 2010 Thesis Title: “Genetic Heterogeneity and Molecular evolution of Human Immunodeficiency Virus Type-1 (HIV-1)’’


Academic Appointments:

•    Visiting Lecturer in Molecular Biology, Department of Biological Sciences, University of Cyprus, Nicosia, Cyprus,  Winter semester 2011
•    Visiting Lecturer in Molecular Biology, Department of Nutrition and Dietics, European University, Nicosia, Eastern Semester 2013                                  

Research Interests

Her research interests are focused in various neurological disorders that Neurology Clinic B’ is involved, like epilepsy, epileptic encephalopathies, migraine, sleep disorders, Alzheimer disease and other types of dementia, Parkinson’s disease and Creutzfeldt‐Jakob disease.

Previous grants:
•    Determination of Resistance in Antiretroviral Drugs and Prediction of Tropism in HIV-1 Strains from Patients in 
Cyprus. Laboratory of Biotechnology and Molecular Virology, Department of Biological Sciences, University of Cyprus (Funded by Research Promotion Foundation, position:Young researcher, Feb 2009 – Feb 2011)
•    Genotype/Phenotype correlation Studies for HbH-disease patients and all the β-thalassaemia patients in Cyprus.
Molecular Genetics Thalassaemia Department, The Cyprus Institute of Neurology and Genetics, Cyprus (Funded by Research Promotion Foundation, position: Researcher, Mar 2013 – Oct 2014) 


Selected Publications:

  1. Kountouris P*, Kousiappa I, Papasavva T, Christopoulos G,  Pavlou E, Petrou M, Feleki X, Karitzie E, Phylactides M, Fanis P, Lederer CW, Kyrri AR, Kalogerou E, Makariou C, Ioannou C, Kythreotis L, Hadjilambi G, Andreou N, Pangalou E, Savvidou I, Angastiniotis M, Hadjigavriel M, Sitarou M, Kolnagou A, Kleanthous M and Christou S: ‘‘The molecular spectrum and distribution of haemoglobinopathies in Cyprus: a 20-year retrospective study’’, Scientific Reports (under submission, reference number: SREP-15-36435).
  2. Fanis P†, Kousiappa I†, Phylactides M and Kleanthous M Genotyping of BCL11A and HBS1L-MYB SNPs associated with fetal haemoglobin levels: a SNaPshot minisequencing approach. BMC Genomics 2014, Feb 6;15(1):108. [Epub ahead of print] (†=equal contribution).
  3. Antoniadou ZA, Kousiappa I, Skoura L, Pilalas D, Metallidis S, Nicolaidis P, Malisiovas N, Kostrikis LG Molecular Epidemiology of HIV Type 1 Infection in Northern Greece (2009-2010): Evidence of a Transmission Cluster of HIV Type 1 Subtype A1 Drug-Resistant Strains Among Men Who Have Sex with Men. AIDS Res Hum Retroviruses 2013, Oct 18, [Epub ahead of print].
  4. Kousiappa I, Achilleos C, Hezka J, Lazarou Y, Othonos K, Demetriades I, Kostrikis LG Near-Full Length Genome Characterization of five Unique Natural Intersubtype Recombinants HIV-1 Isolates: A 3-year Prospective Molecular Epidemiology Study in Cyprus. AIDS Res Hum Retroviruses 2011, May 11, [Epub ahead of print]. 
  5. Demetriou VL, Van de Vijver DAMC, Kousiappa I, Balotta C, Clotet B, Grossman Z, Jorgensen LB, Lepej SZ, Levy I, Nielsen C, Paraskevis D, Poljak M, Roman F, Ruiz L, Schmidt JC, Vandamme AM, Van Laethem K, Vercauteren J, Kostrikis LG Cellular HIV-1 DNA Levels in Drug Sensitive Strains Are Equivalent to Those in Drug Resistant Strains in Newly-Diagnosed Patients in Europe. Plos One 2010, 5, (6), e10976. 
  6. Kousiappa I, Van de Vijver DAMC, Kostrikis LG Near Full-Length Genetic Analysis of HIV Sequences Derived from Cyprus: Evidence of a Highly Polyphyletic and Evolving Infection. AIDS Res Hum Retroviruses 2009, 25, (8): 727-40. 
  7. Kousiappa I, Van de Vijver DAMC, Demetriades I, Kostrikis LG Genetic Analysis of HIV Type 1 Strains from Newly Infected Untreated Patients in Cyprus: High Genetic Diversity and Low Prevalence of Drug Resistance. AIDS Res Hum Retroviruses 2009, 25, (1), 23-35.
  8. Loizidou EZ, Kousiappa I, Zeinalipour-Yazdi CD, Van de Vijver DAMC, Kostrikis LG Implications of HIV-1 M group polymorphisms on integrase inhibitor efficacy and resistance: genetic and structural in silico analyses. Biochemistry 2009, 48, (1), 4-6.
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