Molecular Virology Department

2024

• Karaolia Popi, Quatrocchi Annalisa, Richter Jan, Iakovides C. Iakovos, Christodoulou Christina, Loutsiou Panagiota, Pavlou Pavlos, Kyriakou Marios; Eliades G. Demetrios, Charalambou Christos, Constantinou Elisavet, Tobias Aurelio, Michael G. Stella, Larcou-Yiannakou Angeliki, Nikolopoulos Georgios, Fatta-Kassinos Despo. Leveraging Wastewater: Validating the National-Scale SARS-CoV-2 Surveillance System in Cyprus for Elevated Public Health Surveillance and Enhanced Epidemiological Insight”, Journal of Environmental Chemical Engineering, 2024, 12 (3), 112953.
• Bashiardes S, Christodoulou C. Orally Administered Drugs and Their Complicated Relationship with Our Gastrointestinal Tract. Microorganisms. 2024 Jan 24;12(2):242.

2023

• Ladas P, Porfyridis I, Tryfonos C, Ioannou A, Adamide T, Christodoulou C, Richter J. Aetiology of Community-Acquired Pneumonia and the Role of Genetic Host Factors in Hospitalized Patients in Cyprus. Microorganisms. 2023 Aug 10;11(8):2051. doi: 10.3390/microorganisms11082051.
• Rafail Konatzii, Fabian Schmidt-Ott, Lakis Palazis, Panagiotis Stagianos, Maria Foka, Jan Richter, Christina Christodoulou, Jean Sciare and Michael Pikridas. Exposure to Airborne SARS-CoV-2 in Four Hospital Wards and ICUs of Cyprus. A Detailed Study Accounting for Day-to-Day Operations and Aerosol Generating Procedures. Heliyon 2023 Mar;9(3):e13669.
• Lambrianides A, Deeba E, Hadjiagapiou M, Pantzaris M, Krashias G, Christodoulou C. SARS-CoV-2-specific antibody responses following BNT162b2 vaccination in individuals with multiple sclerosis receiving different disease-modifying treatments. Front Neurol. 2023 Feb 24;14:1092999. doi: 10.3389/fneur.2023.1092999. eCollection 2023.

2022

• Jan Richter, Dana Koptides, Christina Tryfonos, Denise Alexandrou and Christina Christodoulou. Introduction, Spread and Impact of the SARS-CoV-2 Omicron Variants BA.1 and BA.2 in Cyprus. Microorganisms 2022, 10(9), 1688.
• Krashias G, Pafiti A, Deeba E, Christodoulou C, Pantzaris M, Lambrianides SARS CoV- 2 vaccination induces antibodies against cardiolipin A. BMC Res Notes. 2022 Sep 7;15(1):292.
• Deeba E, Krashias G, Constantinou A, Koptides D, Lambrianides A, Christodoulou C. Evaluation of S1RBD-Specific IgG Antibody Responses following COVID-19 Vaccination in Healthcare Professionals in Cyprus: A Comparative Look between the Vaccines of Pfizer-BioNTech and AstraZeneca. Microorganisms. 2022; 10(5):967.

2021

• Krashias G, Deeba E, Constantinou A, Hadjiagapiou M, Koptides D, Richter J, Tryfonos C, Bashiardes S, Lambrianides A, Loizidou MA, Hadjisavvas A, Panayiotidis MI, Christodoulou C. Characterization of IgG Antibody Response against SARS-CoV-2 (COVID-19) in the Cypriot Population. Microorganisms. 2021 Dec 31;10(1):85.
• Kagiava A, Richter J, Tryfonos C, Leal-Julià M, Sargiannidou I, Christodoulou C, Bosch A, Kleopa KA. Efficacy of AAV serotypes to target Schwann cells after intrathecal and intravenous delivery. Sci Rep. 2021 Dec 2;11(1):23358.
• Anastasis Oulas, Jan Richter, Maria Zanti, Marios Tomazou, Kyriaki Michailidou, Kyproula Christodoulou, Christina Christodoulou, George M. Spyrou. In depth analysis of Cyprus-specific mutations of SARS-CoV-2 strains using computational approaches. BMC Genom Data 22, 48 (2021).
• Jan Richter, Pavlos Fanis, Christina Tryfonos, Dana Koptides, George Krashias, Stavros Bashiardes, Andreas Hadjisavvas, Maria Loizidou, Anastasis Oulas, Denise Alexandrou, Olga Kalakouta, Mihalis I. Panayiotidis, George M. Spyrou, Christina Christodoulou. Molecular Epidemiology of SARS-CoV-2 in Cyprus. PLoS One. 2021 Jul 21;16(7):e0248792.
• Despina Varvatsi, Jan Richter, Christina Tryfonos, Marios Pantzaris, Christina G Christodoulou. Association of Epstein-Barr virus latently expressed genes with multiple sclerosis. Mult Scler Relat Disord. 2021 May 7;52:103008.

2020

• Deeba E, Lambrianides A, Pantzaris M, Krashias G, Christodoulou C. The expression profile of virus-recognizing toll-like receptors in natural killer cells of Cypriot multiple sclerosis patients. BMC Res Notes. 2020 Sep 29;13(1):460
• Erik Alm, Eeva K Broberg, Thomas Connor, Emma B Hodcroft, Andrey B Komissarov, Sebastian Maurer-Stroh, Angeliki Melidou, Richard A Neher, Áine O'Toole, Dmitriy Pereyaslov, WHO European Region sequencing laboratories and GISAID EpiCoV group. Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020 Euro Surveill. 2020 Aug;25(32):2001410.

2019

• Deeba E, Koptides D, Gaglia E, Constantinou A, Lambrianides A, Pantzaris M, Krashias G, Christodoulou C. Evaluation of Epstein-Barr virus-specific antibodies in Cypriot multiple sclerosis patients. Mol Immunol. 2019 Jan;105:270-275. doi: 10.1016/j.molimm.2018.12.010

2018

• Kagiava A, Karaiskos C, Richter J, Tryfonos C, Lapathitis G, Sargiannidou I, Christodoulou C, Kleopa KA. Intrathecal gene therapy in mouse models expressing CMT1X mutations. Hum Mol Genet. 2018 Feb 14.
• Dalitis S, Filippidou N, Krashias G, Christodoulou C, Pantzaris M, Lambrianides A. The possible role of an autoimmune mechanism in the etiopathogenesis of Parkinson's disease. J Clin Neurosci. 2018 Aug;54:63-68.

2017

• Richter J, Tryfonos C, Tourvas A, Floridou D, Paphitou NI, Christodoulou C. 2017. Complete genome sequence of West Nile virus (WNV) from the first human case of neuroinvasive WNV infection in Cyprus. Genome Announc 2017 Oct 26;5(43).
• Koliou MG, Kakourou T, Richter J, Christodoulou C, Soteriades ES. Mycoplasma pneumoniae as a cause of vulvar ulcers in a non-sexually active girl: a case report. J Med Case Rep. 2017 Jul 9;11(1):187.
• Krashias G, Koptides D, Christodoulou C. HPV prevalence and type distribution in Cypriot women with cervical cytological abnormalities. BMC Infect Dis. 2017 May 16;17(1):346
• Paphitou NI, Tourvasa A, Floridou D, Richter J, Tryfonos C, Christodoulou C. The first human case of neuroinvasive West Nile virus infection identified in Cyprus. J Infect Public Health. 2017 Feb 21.
• Georgiou E, Sidiropoulou K, Richter J, Papaneophytou C, Sargiannidou I, Kagiava A, von Jonquieres G, Christodoulou C, Klugmann M, Kleopa KA. Gene therapy targeting oligodendrocytes provides therapeutic benefit in a leukodystrophy model. Brain. 2017 Jan 18.

2016

• Kagiava A, Sargiannidou I, Theophilidis G, Karaiskos C, Richter J, Bashiardes S, Schiza N, Nearchou M, Christodoulou C, Scherer SS, Kleopa KA. Intrathecal gene therapy rescues a model of demyelinating peripheral neuropathy. Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):E2421-9.
• Richter J, Panayiotou C, Tryfonos C, Koptides D, Koliou M, Kalogirou N, Georgiou E, Christodoulou C. Aetiology of Acute Respiratory Tract Infections in Hospitalised Children in Cyprus. PLoS One. 2016 Jan 13;11(1):e0147041.
• Filippidou N, Krashias G, Pericleous C, Rahman A, Ioannou Y, Giles I, Demetriou C, Anatolitou A, Christodoulou C, Pantzaris M, Lambrianides A. The association between IgG and IgM antibodies against cardiolipin, β2-glycoprotein I and Domain I of β2-glycoprotein I with disease profile in patients with multiple sclerosis. Mol Immunol. 2016 Jul;75:161-7.

2015

• Sargiannidou I, Kagiava A, Bashiardes S, Richter J, Christodoulou C, Scherer SS, Kleopa KA (2015). Intraneural GJB1 gene delivery improves nerve pathology in a model of X-linked Charcot-Marie-Tooth disease. Ann Neurol. 2015 Aug;78(2):303-16.

2014

• Kagiava A, Sargiannidou I, Bashiardes S, Richter J, Schiza N, Christodoulou C, Gritti A, Kleopas K (2014). Gene delivery targeted to oligodendrocytes using a lentiviral vector. J Gene Med. Nov 12. doi: 10.1002/jgm.2813 
• Richter J, Nikolaou E, Panagiotou C, Tryfonos C, Koliou M, Christodoulou C (2014). Molecular epidemiology of rhinoviruses in Cyprus over three consecutive seasons. Epidemiol Infect. Nov 12:1-8. 
• Panayiotou C, Richter J, Koliou M, Kalogirou N, Georgiou E, Christodoulou C (2014). Epidemiology of respiratory syncytial virus in children in Cyprus during three consecutive winter seasons (2010-2013): age distribution, seasonality and association between prevalent genotypes and disease severity. Epidemiol Infect. Jan 24:1-6.
• Koliou M, Karaoli E, Soteriades ES, Pavlides S, Bashiardes S, Christodoulou C. Acute hepatitis and myositis associated with Erythema infectiosum by Parvovirus B19 in an adolescent. BMC Pediatr. 2014 Jan 13;14:6. doi: 10.1186/1471-2431-14-6.

2013

• Panayiotou C, Richter J, Bashiardes S, Koptides D, Tryfonos C, Christodoulou C (2013). Molecular epidemiology of influenza A virus infection in Cyprus in four consecutive seasons (2009 pandemic-2013). Epidemiol Infect. Oct 24:1-9.
• Richter J, Tryfonos C, Panagiotou C, Nikolaou E, Koliou M, Christodoulou C (2013). Newly emerging C group enteroviruses may elude diagnosis due to a divergent 5'-UTR. Int J Infect Dis. 2013 Dec;17(12):e1245-8 
• Henquell C, Mirand A, Richter J, Schuffenecker I, Böttiger B, Diedrich S, Terletskaia-Ladwig E, Christodoulou C, Peigue-Lafeuille H, Bailly JL (2013). Phylogenetic patterns of human coxsackievirus B5 arise from population dynamics between two genogroups and reveal evolutionary factors of molecular adaptation and transmission. J Virol. Nov;87(22):12249-59

2011

• Richter J, Tryfonos C, Christodoulou C (2011). Circulation of enteroviruses in Cyprus assessed by molecular analysis of clinical specimens and sewage isolates. J Appl Microbiol. Aug;111(2):491-8.
• Tryfonos C, Richter J, Koptides D, Yiangou M, Christodoulou CG( 2011). Molecular typing and epidemiology of enteroviruses in Cyprus, 2003-2007. J Med Microbiol. Oct;60(Pt 10):1433-40.
• Bashiardes S, Koptides D, Pavlidou S, Richter J, Stavrou N,  Papageorgiou G, Christodoulou C (2011). Analysis of enterovirus and adenovirus presence in swimming pools in Cyprus from 2007-2008. Water Science & Technology Vol 63(11):2674–2684.