Stavroulla Xenophontos

Academic Staff

Current Position

Scientist, Department of Cardiovascular Genetics and the Laboratory of Forensic Genetics

The Cyprus Institute of Neurology & Genetics


  • BSc Degree – Microbiology, University College London, UoL, UK,  graduated in 1988
  • PhD Degree - University College London UoL, UK,  Title of thesis: Genetic and Physical Mapping in the Terminal Region of Human Chromosome 1p Awarded  in 1994


Academic Appointments:

  1. Associate Faculty – CSMM 2016 until present

Research Interests

  • Service provision includes Thrombophilia screening and mutation detection in genes causing familial hypercholesterolaemia.
  • Coordinating all the daily activities of the Laboratory of Forensic Genetics Quality Assurance Programme in accordance with the ISO17025 QA Standard.
  • Epidemiological studies to identify genetic and environmental risk factors which contribute to cardiovascular disease.
  • Genetic studies to identify genetic factors which contribute to endurance athletics.
  • Genetic  studies to identify factors involved in touch DNA transfer. 
  • Epigenetic biofluid identification methods.


  • Appointed Quality Manager of The Laboratory of Forensic Genetics by the LabFoG Director (2007).
  • Appointed member of the bioethics review committee for biomedical research on human beings and their biological substances by the Cyprus National Bioethics Committee (CNBC). 28/11/2008 – 27/11/2009
  • Appointed member and elected chairwoman of the bioethics review committee for biomedical research on human beings and their biological substances by the Cyprus National Bioethics Committee (CNBC). 01/12/2011-30/11/2013.


Selected Publications:


  1. Manoli P,  Antoniou A, Bashiardes E, Xenophontos S,  Photiades M,, Stribley V, Mylona M, Demetriou Ch, Cariolou AM (2015). Sex-specific age association with primary DNA transfer. Int J Legal Med. DOI 10.1007/s00414-015-1291-2.
  2. Xenophontos S, Christofi V, Iosif G, Polycarpou P, Manoli P, Cariolou MA (2014).  Internal validation of the QIAamp DNA Investigator kit QIAamp 96 DNA Swab BioRobot kit and the BioRobot Universal System for DNA extraction from reference and crime scene samples.  Forensic Science International: Genetics 14: e8-e10.
  3. 3) Diakou M, Miltiadous G, Xenophontos SL, Manoli P, Cariolou MA, Elisaf M. Spectrum of LDLR gene mutations, including a novel mutation causing familial hypercholesterolaemia, in North-western Greece (2011). Eur J Intern Med 22(5):0, PMID 21925044.
  4. Diakou M, Miltiadous G, Xenophontos S, Cariolou M, Heta N, Korita I, Bulo A, Refatllari E, Bairaktari E, Elisaf M (2010). Characterization of low density lipoprotein receptor (LDLR) gene mutations in Albania. Arch Med Sci. Apr 30; 6(2):198-200. PMID: 22371747.
  5. Saunders CJ, September AV, Xenophontos SL, Cariolou MA, Anastassiades LC, Noakes TD, Collins M No Association of the ACTN3 gene R577X polymorphism with endurance performance in Ironman Triathlons. Ann Hum Genet. (2007) Nov;71 (Pt 6):777-81. PMID: 17627799.
  6. Xenophontos Stavroulla, Hadjivassiliou Marilena, Karagrigoriou Alexandros, Demetriou Nafsika, Miltiadous George, Marcou Ioannis, Elisaf Moses, Mikhailidis Dimitri P, Cariolou Marios A Low HDL Cholesterol, Smoking and IL-13 R130Q Polymorphism are Associated with Myocardial Infarction in Greek Cypriot Males. A Pilot Study. (2008). Open Cardiovasc Med J, PMID 18949100.
  7. Xenophontos SL, Pierides A, Demetriou K, Avraamides P, Manoli P, Ayrton N, Skordis N, Anastasiadou V, Miltiadous G, Cariolou MA (2000). Geographical clustering of low density lipoprotein receptor gene mutations (C292X; Q363X; D365E & C660X) in Cyprus. Hum Mutat. Apr;15(4):380.
  8. Xenophontos S, Constantinides R, Hayashi T, Mochizuki T, Somlo S, Pierides A, Deltas CC (1997). A translation frameshift mutation induced by a cytosine insertion in the polycystic kidney disease 2 gene (PDK2). Hum Mol Genet. Jun;6(6):949-52.
  9. Constantinides R, Xenophontos S, Neophytou P, Nomura S, Pierides A, Deltas CC (1997). New amino acid polymorphism, Ala/Val4058, in exon 45 of the polycystic kidney disease 1 gene: evolution of alleles. Hum Genet. May;99(5):644-7.
  10. Mochizuki T, Wu G, Hayashi T, Xenophontos SL, Veldhuisen B, Saris JJ, Reynolds DM, Cai Y, Gabow PA, Pierides A, Kimberling WJ, Breuning MH, Deltas CC, Peters DJ, Somlo S (1996). PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein. Science. May 31;272(5266):1339-42.
winner aashe copernicus