Founder, Department of Electron Microscopy and Molecular Pathology (renamed to CGTUP)
The Cyprus Institute of Neurology & Genetics
E-mail: [email protected]
BSc Honours degree, in Biochemistry/Physiology, University of London. 1977
PhD, Faculty of Medicine. Department of Oral Pathology, King’s College Schools of Medicine and Dentistry.1982,
Thesis title: Nerve induced secretory processes in rabbit submandibular glands.
1982 : Lecturer in Biochemistry, Medical School at King’s College Hospital, London.
1985: Research Associate and Head of the Electron Microscope Department, at King Saud University, Riyadh Saudi Arabia.
1991: Senior Scientist, at the Cyprus Institute of Neurology and Genetics.
2012 :Professor, The Cyprus School of Molecular Medicine
2012: Co-ordinator of the programme on Molecular Medicine
2014: Dean of The Cyprus School of Molecular Medicine
The department has pioneered the work on cancer genetics in Cyprus with emphasis on the characterization of mutations in familial cancer predisposition syndromes. Our research interests include the epidemiology and molecular pathology of cancer, pharmacogenomics, cancer proteomics and the genetics of mitochondrial Myopathies.
Professor Kyriacos Kyriacou received his BSc degree in Biochemistry from the University of London in 1977 and his PhD from King’s College Medical School, in 1982 where he was also appointed as lecturer. Since 1991 he is working at CING as a Senior Scientist and Head of the Department of Electron Microscopy/Molecular Pathology. He is the founder of this department , which offers a centralized diagnostic ultrastructural service, as well as an extensive range of cancer genetic services, that diagnose cancer predisposition syndromes, as well identify actionable genetic targets for personalized medicine and oncogenetics. He is an internationally acclaimed expert on Electron Microscopy, as well as n Cancer Genetics. The department has graduated six PhDs and more than 20 MSc students.
Dr Kyriacou initiated the research into cancer genetics, with emphasis on characterizing mutations in predisposition genes in Cypriot families and is now leading one of the main teams in Cyprus, involved in cancer research. His main research interests include the genetic epidemiology and molecular pathology of cancer, ciliary disorders and cancer proteomics. He is the co-ordinator of several research grants and has obtained more than 8,000,000 euros in competitive funding and has authored more than 130 peer reviewed articles. He participates as a representative of Cyprus in several Societies and advisory Scientific committees in Europe. He was appointed by the Cyprus Research Promotion Foundation as the representative of Cyprus, in the EU-COST programme, in the BMBS (Biomedicine and Biomolecular Sciences) domain. He is an active member of the of the Electron Microscopy working group which is part of the European Society of Pathology. He serves as a reviewer/evaluator for several scientific journals and research funding bodies. He has organized several scientific conferences, both at National and International levels and has been invited to deliver many lectures both locally and abroad. His latest achievement is the Establishment of the Translational Facility at CING, which creates new important avenues for research on proteomics and on improving our understanding on the molecular mechanisms of many complex diseases like cancer.
- Biomarkers of systemic lupus erythematosus identified using mass spectrometry‐based proteomics: a systematic review. Orthodoxia Nicolaou, Andreas Kousios, Andreas Hadjisavvas, Bernard Lauwerys, Kleitos Sokratous, Kyriacos Kyriacou, J Cell Mol Med. 2017 May; 21(5): 993–1012. Published online 2016 Nov 23.
- Eleni Fella, Kleitos Sokratous, Revekka Papacharalambous, Kyriacos Kyriacou, Joy Phillips, Sam Sanderson, Elena Panayiotou, Theodoros Kyriakides. Pharmacological Stimulation of Phagocytosis Enhances Amyloid Plaque Clearance; Evidence from a Transgenic Mouse Model of ATTR Neuropathy. Front. Mol. Neurosci. 10:138, 2017; doi: 10.3389/fnmol.2017.00138.
- Sadr‑ul Shaheed, Catherine Tait, Kyriacos Kyriacou, Richard Linforth, Mohamed Salhab and Chris Sutton, Evaluation of nipple aspirate fluid as a diagnostic tool for early detection of breast cancer. Clin Proteom (2018) 15:3, 1-15
- Ekatherine Prokopiou, Panagiotis Kolovos, Maria Kalogerou, Anastasia Neokleous, Orthodoxia Nicolaou, Kleitos Sokratous, Kyriacos Kyriacou, and Tassos Georgiou. Omega-3 Fatty Acids Supplementation: Therapeutic Potential in a Mouse Model of Stargardt Disease. IOVS June 2018,Vol. 59 , No. 7 , 2757-67.
- Eleni Frangou, Agathi Varnavidou-Nicolaidou, Panayiotis Petousis, Andreas Soloukides, Elena Theophanous, Isavella Savva, Nicos Michael, Elpida Toumasi, Dora Georgiou, Galatia Stylianou, Richard Mean, Natasa Anastasiadou, Yiannis Athanasiou, Michalis Zavros, Kyriacos Kyriacou, Constantinos Deltas and Vassilis Hadjianastassiou. Clinical course and outcome after kidney transplantation in patients with C3 glomerulonephritis due to CFHR5 nephropathy. Nephrol Dial Transplat (2019) 1-9.