Selected Publications

Mastroyiannopoulos N, Feldman M, Mahadevan MS, Uney JB and Phylactou LA. Woodchuck post-transcriptional regulatory element enhances nuclear export of myotonic dystrophy transcripts. EMBO Reports. 6(5), 458–463, 2005.

Toshiyuki Yoshida, Leonidas Phylactou, James Uney, Isao Ishikawa, Kazuhiro Eto and Sachiko Iseki. Twist is involved in establishment of the coronal suture. Journal of Anatomy. 206(5):437-44, 2005.

Ioannis Bantounas, Colin PJ Glover, Sachiko Iseki, Leonidas A Phylactou, James B Uney. Assesing adenoviral hammerhead ribozyme and shRNA cassettes in primary neurons: inhibition of endogenous Caspase-3 activity and protection from apoptotic cell death. Journal of Neuroscience Research. 79(5):661-9, 2005.

Bantounas I, Phylactou LA, Uney JB. RNA Interference And The Use Of siRNA To Study Gene Function In Mammalian Systems. Journal of Molecular Endocrinology. 2004, 33 (3), 545-557.

Theoni K. Georgiou, Maria Vamvakaki, Costas S. Patrickios, Edna N. Yamasaki and Leonidas A Phylactou. Nanoscopic Cationic Methacrylate Star Homopolymers: Synthesis by Group Transfer Polymerization, Characterization and Evaluation as Transfection Reagents. Biomacromolecules 2004, 5(6), 2221-2229.

Evdokia Kastanos, Eleni Hjiantoniou and Leonidas A Phylactou. Restoration of protein synthesis in pancreatic cancer cells by trans-splicing ribozymes. Biochemical and Biophysical Research Communications. 322(3) 930-934, 2004.

Eleni Hjiantoniou, Sachiko Iseki, James B Uney and Leonidas A Phylactou. DNazyme-mediated cleavage of Twist transcripts and increase in cellular apoptosis. Biochemical and Biophysical Research Communications, 300(1) 178-181, 2003.

Despina Maniotis, Matthew Wood, Harry Charlton and Leonidas Phylactou. The application of hammerhead ribozymes to the down-regulation of nNOS gene expression. Neuroscience Letters 329(1) p. 81-85, 2002.

Leonidas A Phylactou. Ribozyme and peptide nucleic acid – based gene therapy. In Advanced