Associate Professor
Current Position
Senior Scientist, Head of the Department of Biochemical Genetics
Associate Professor
Course Coordinator of MG104: Biochemical Basis of Genetic Diseases
The Cyprus Institute of Neurology & Genetics
Research Interests
- Lysosomal glycogen transport and metabolism
Biography
Completed undergraduate studies in Biology at the University of Göttingen / Germany and received his PhD in 2001 from the same university for a thesis performed at the Max-Planck Institute of Biophysical Chemistry in the field of developmental and cell biology. From 2002-2006 he was a post-doctoral fellow at the Department of Biology of the University of Crete where he investigated the role of a new family of extracellular matrix proteins in epithelial basement membranes in the mouse embryo. In September 2008 he joined the Department of Biochemical Genetics of the CING where he is currently involved in diagnostic and research activities related to inherited metabolic disorders.
Selected Publications:
- Demetriadou, A., Morales-Sanfrutos, J., Nearchou, M., Baba, O., Kyriacou, K., Tate, EW., Drousiotou, A., Petrou, PP.: “Mouse Stbd1 is N-myristoylated and affects ER-mitochondria association and mitochondrial morphology”. J. Cell Sci. (2017), 130: 903-915
- Petrou, PP., Pantzaris, M., Dionysiou, M., Drousiotou, A., Kyriakides, T.: “Minimally symptomatic McArdle disease, expanding the genotype-phenotype spectrum”. Muscle Nerve (2015), 52:891-895
- Petrou, P., Pavlakis, E., Dalezios, Y., Chalepakis G: “Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.” Matrix Biol. (2007), 26: 652-658
- Petrou, P., Chiotaki, R., Dalezios, Y., Chalepakis, G.: “Overlapping and divergent localization of Frem1 and Fras1 and its functional implications during mouse embryonic development.” Exp. Cell Res. (2007), 313: 910-920
- Petrou, P., Pavlakis, E., Dalezios, Y., Galanopoulos, VK., Chalepakis, G.: “Basement membrane distortions impair lung lobation and capillary organization in the mouse model for Fraser syndrome.” J. Biol. Chem. (2005), 280: 10350-10356
- Vrontou, S., Petrou, P., Meyer, BI., Galanopoulos, VK., Imai, K., Yanagi, M., Chowdhury, K., Scambler, PJ., Chalepakis, G.: “Fras1 deficiecy results in cryptophthalmos, renal agenesis and blebbed phenotype in mice.” Nat. Genet. (2003), 34: 209-214
- Goudreau, G., Petrou, P., Reneker L. W, Graw, J., Loster, J., Gruss, P. “Mutually regulated expression of Pax6 and Six3 and its implications for the Pax6 haploinsufficient lens phenotype.” Proc. Natl Acad. Sci. USA, (2002), 99: 8719-8724
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