CING Lectures: From biomarker research to...

From biomarker research to personalized medicine using circulating tumor DNA

Maria Neofytou, Ph.D.
Postdoctoral Research Associate, Rosenfeld Lab, Cancer Research UK, University of Cambridge, United Kingdom 
https://zoom.us/j/3820891216

Wednesday, 29th September 2021
16:00 – 17:00 h (Cypriot time)

Talk Summary
Molecular profiling from liquid biopsy, in particular circulating tumor DNA (ctDNA), represents an attractive alternative to tissue biopsies for the detection of actionable targets and tumor monitoring. Approaches for ctDNA analysis range from hotspot mutation assays to whole-genome sequencing methods. The aim is to develop assays that achieve high sensitivity across a large number of mutations. Despite massive progress in the field, the utilization of ctDNA in the management of cancer patients has yet to achieve routine implementation in the clinic. In this talk, several studies for ctDNA analysis will be presented with focus on somatic copy number analysis (SCNAs) from plasma for earlier cancer detection.

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