(last updated April 2012)

2012

Scherer SS, Kleopa KA (2011) X-linked Charcot-Marie-Tooth Disease. J Peripheral Nervous System, in press.

Irani SR,* Pettingill P,* Kleopa KA,* Schiza N, Waters P, Mazia C, Zuliani L, Watanabe O, Lang B, Buckley C, Vincent A (2012) Morvan’s syndrome: clinical and serological observations in 29 cases. Annals of Neurology, Mar 9. doi: 10.1002/ana.23577 (*:joint first authors)

Markoullis K, Sargiannidou I, Gardner C, Hadjisavvas A, Reynolds R, Kleopa KA (2012) Disruption of oligodendrocyte gap junctions in experimental autoimmune encephalomyelitis. Glia, Mar 27. doi: 10.1002/glia.22334 .

Markoullis K, * Sargiannidou I, * Schiza N, Hadjisavvas A, Roncaroli F, Reynolds R, Kleopa KA (2012) Gap junction pathology in multiple sclerosis lesions and in normal appearing white matter. Acta Neuropathologica, Apr 7. [Epub ahead of print] PMID: 22484441

2011

Kleopa KA (2011) Autoimmune Channelopathies of the Nervous System. Curr Neuropharmacol. 9:458-467.

Kleopa KA (2011) The role of gap junctions in Charcot-Marie-Tooth disease J Neurosci, 31:17753-17760.

 2010

Spanaki C, Zaganas I, Kleopa KA, Plaitakis A (2010) Human GLUD2 Glutamate Dehydrogenase is Expressed in Mitochondria of Neural and Testicular Supporting Cells, J. Biol. Chem. 285:16748-56.

Sargiannidou, I, Markoullis, K, Kleopa KA (2010) Molecular mechanisms of gap junction mutations in myelinating cells. Histol Histopathol. 25:1191-1206.

Nicolaou P, Zamba-Papanicolaou E, Koutsou P, Kleopa KA, Georghiou A, Hadjigeorgiou G, Papadimitriou A, Kyriakides T, Christodoulou K (2010) Charcot-Marie-Tooth disease in the Cypriot population: epidemiological, clinical and genetic characteristics.  Neuroepidemiology, 35(3):171-177.

Kleopa KA, Orthmann-Murphy JL, Sargiannidou, I (2010) Gap junction disorders of myelinating cells, Reviews Neurosci, 21 (5): 397-419.

Vavlitou, N, Sargiannidou, I, Markoullis, K, Kyriacou K, Scherer SS, Kleopa KA (2010) Axonal pathology precedes demyelination in a mouse model of CMT1X neuropathy, J Neuropathol Exp Neurol, 69 (9): 945-958.

Irani SR, Alexander S, Waters P, Kleopa KA, Pettingill P, Zuliani L, Peles E, Buckley C, Lang B, Vincent A (2010) Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-2-associated protein in limbic encephalitis, Morvan’s syndrome and acquired neuromyotonia. Brain, 133:2734-2748.

2009

Sargiannidou I, Vavlitou N, Aristodemou S, Hadjisavvas A, Kyriacou K, Scherer SS, Kleopa KA (2009). Connexin32 mutations cause loss of function in Schwann cells and oligodendrocytes leading to PNS and CNS myelination defects. J Neurosci, 29:4736-4749.

Sargiannidou, I, Markoullis, K, Kleopa KA: Molecular mechanisms of gap junction mutations in myelinating cells (2009) Histol Histopathol, in press.

Kleopa KA, Orthmann-Murphy JL, Sargiannidou, I (2009) Gap junction disorders of myelinating cells, Reviews Neurosci, in press.

Mintchev N, Zamba-Papanicolaou E, Kleopa KA, Christodoulou K (2009) A novel ALS2 splice-site mutation in a Cypriot Juvenile Primary Lateral Sclerosis family. Neurology, 72:28-32.

Kleopa KA, Natsiopoulos K (2009) Acute cervical radiculopathies in spontaneous intracranial hypotension. J Neurology, 256(3):499-501

Sargiannidou I, Ahn M, Enriquez AD, Peinado A, Reynolds R, Abrams CK, Scherer SS, Kleopa KA (2008) Human oligodendrocytes express Cx31.3: function and interactions with Cx32 mutants. Neurobiol Dis 30:221-233.

Savvaki M, Panagiotaropoulos T, Stamatakis A, Sargiannidou I, Karatzioula P, Watanabe K, Stylianopoulou F, Karagogeos D, Kleopa KA (2008) Impairment of learning and memory in TAG-1 deficient mice associated with shorter CNS internodes and disrupted juxtaparanodes. Mol Cell Neurosci 39:478-490.

2007

Bataller L, Kleopa KA, Wu G, Rossi JE, Rosenfeld MR, Dalmau J (2007) Autoimmune Limbic Encephalitis in 39 Patients: Immunophenotypes and Outcomes. J Neurol Neurosurg Psychiatry 78 381-385.

2006

Kleopa KA, Scherer, S.S (2006) Molecular genetics of X-linked Charcot-Marie-Tooth disease. Neuromolecular Med, 8:107-122. link to PDF

Kleopa KA, Elman L, Lang B, Vincent A, Scherer SS (2006) Neuromyotonia and limbic encephalitis sera target mature Shaker-type K+ channels: subunit specificity correlates with clinical manifestations. Brain 129:1570-1584. link to PDF

Vincent A, Lang B, Kleopa KA (2006) Autoimmune channelopathies and related neurological disorders. Neuron 52:123-138. link to PDF

Kleopa KA, Drousiotou A, Mavrikiou E, Ormiston A, Kyriakides T (2006). Naturally occurring utrophin correlates with disease severity in Duchenne Muscular Dystrophy. Hum Mol Genet, 15:1623-8. link to PDF.

Kleopa KA, Zamba-Papanicolaou E, Alevra X, Nicolaou P, Georgiou D-M, Hadjisavvas A, Kyriakides T, Christodoulou K (2006) Phenotypic and cellular expression of two novel connexin32 mutations causing CMT1X. Neurology 66:396-402.

2004

Kleopa KA, Orthmann JL, Enriquez A, Paul DL, Scherer SS (2004) Unique distribution of gap junction proteins connexin29, connexin32, and connexin47 in oligodendrocytes. Glia 47:346-357. link to PDF

Devaux J., Kleopa K.A., Cooper E.C., Scherer S.S., (2004) KCNQ2 is a nodal K+ channel, J Neurosci,24:1236-1244.