Electron Microscopy and Molecular Pathology Department

The department of Electron Microscopy/Molecular Pathology provides a spectrum of diagnostic services which are based on two main laboratory disciplines. The first one is concerned with the examination of biopsies with the electron microscope and aims to provide additional diagnostic information for diagnosing a range of diseases. These include neuromuscular, kidney and skin disorders as well as a spectrum of rare diseases and syndromes, such as ciliary disorders, where ultrastructural pathology is essential for accurate diagnosis. The second discipline is concerned with the application of molecular genetics for diagnosing familial predisposition to cancer such as the breast/ovarian and colorectal cancer syndromes. A recent development is the application of pharmacogenetics in order to detect the presence of mutated genes, which constitute the target for many upcoming therapies in oncology. In addition to carrying out the above diagnostic services the department has established itself as a national center for executing research programs, that focus on cancer epidemiology and cancer genetics.